Los Angeles' Jaime Villarreal scored in the 40th minute to provide the only goal as the Galaxy handed Real Salt Lake its first preseason loss on Tuesday in Carson, Calif.
RSL had won once and tied five times in preseason play heading into Tuesday. The team made wholesale personnel changes in the second half after giving up the lone goal late in the first.
Emanuel Boateng crossed to Villarreal in the box for the game's lone score. RSL had a chance to equalize in the 81st minute when Albert Rusnak sent a corner kick into the box, but a shot went over the crossbar.
RSL will play its final preseason match on Friday in California, against Armenian champions Alashkert. Real will open the 2017 regular season on March 4 against Toronto FC at Rio Tinto Stadium.