States of emergencies have already been declared and schools have already been closed ahead of wintry weather mix that is expected to continue to batter much of the South on Wednesday.
Heavy rain, snow, and temperatures 20 to 30 degrees below zero were forecast for several states. The wintry mix of precipitation was expected from northern Texas eastward across the Gulf states and into the Carolinas, according to the National Weather Service.
By early Thursday, forecasters said, relief is expected.
The latest storm comes after several others have hit much of the South, Mid-Atlantic Midwest and East Coast. Here's a look at how winter weather has affected some areas:
MILESTONE FOR BOSTON
With 1.9 inches of snow overnight, Boston has now received more than 100 inches of snow this winter.
The National Weather Service reported Wednesday that the snowfall as recorded at Logan International Airport is now 101.8 inches for the season.
That makes this winter the second snowiest on record, behind only the 107.6 inches recorded in the winter of 1995-96.
'BE GREAT NEIGHBORS'
With the new weather system coming in, Tennessee Gov. Bill Haslam urged people to check on their neighbors as the death toll from last week's ice storm climbed.
Haslam and state emergency officials flew over parts of the state Tuesday to survey the damage. At least 30 people have died across the state as a result of the ice storm and frigid temperatures. At least 10 are believed to have died as a result of hypothermia.
"The best thing we can do is ask people to be great neighbors," Haslam said.
Many people, especially the elderly, either don't have the resources to leave their homes or simply don't want to go somewhere else, he said. The Tennessee National Guard and other agencies have been doing welfare checks.
Some of the victims have died in their homes after being without heat. A number of people have been discovered dead outside their home, including two elderly people who are believed to have fallen and to have suffered from extreme exposure because they couldn't get up.
With the storm approaching Wednesday morning, only about 30 flights had been canceled nationwide, according to the tracking website FlightAware.
Dallas-Fort Worth International Airport maintenance crews treated runways, taxiways and all roadways in anticipation of several inches of snow.
MORE THAN MILK AND BREAD
Some folks are stocking up on more than pantry staples — they're headed for the liquor.
Customers at Riverside Wine & Spirits in Chattanooga, Tennessee, told WRCB-TV (http://bit.ly/1DphvwG) that they came in Tuesday to get alcohol before more snow and ice hit the region.
Worker Jamie Campbell said customers also stocked up last Friday before that snowstorm hit. Even though the store closed early due to the weather, Campbell said sales were still about $5,000 more than on a normal Friday night.
As snow and frigid temperatures continue in Ohio, communities in parts of the state are running short on road salt, city officials said.
Some cities have waited weeks for hundreds of tons of ordered salt, the Northeast Ohio Media Group reported (http://bit.ly/1DQsL6q).
The region has recorded nearly 60 inches of snow since November. Lower-than average temperatures have made snow harder to melt and roads more difficult to clear.
For some cities, a serious salt problem is just one more snowfall away.
"We have enough to last this next week, but if it keeps consistently snowing it's going to be difficult," Middleburg Heights Service Director Jim Herron said.