LOUISVILLE, Ky. — Lawrence Wilson returned an interception 45 yards for a touchdown with less than three minutes to play to give Connecticut a 26-21 victory over Louisville on Friday night.

Donald Brown ran for 190 yards and a touchdown for the Huskies (5-0, 1-0 Big East), who rode the legs of the nation's leading rusher to stay in it after starting quarterback Tyler Lorenzen was sidelined by a foot injury. Sophomore Zach Frazer threw for 90 yards and a touchdown in place of Lorenzen and wisely let Brown do most of the work.

Louisville (2-2, 0-1) moved the ball effortlessly at times and piled up 508 yards of total offense but squandered several opportunities to put the game away.

Redshirt freshman running back Victor Anderson ran for 100 yards and had a touchdown running and receiving, and Bilal Powell added 112 yards and a touchdown, but Louisville had trouble throwing the ball after quarterback Hunter Cantwell injured his left ankle in the third quarter.