Peripheral artery disease is a concern for people with high cholesterol, diabetes and high blood pressure.

Often described as "poor circulation," it occurs when the large leg arteries narrow and restrict blood flow, which can result in skin ulcers and lead to amputation.

A University of Utah physician, Dr. Mark Sarfati, is part of a national research study to see if an investigational medication that promotes new blood vessel growth can delay the time of amputation and/or death.

To participate, an individual must be at least 50 with stable skin ulcers or noninfected gangrene on a foot or leg, diagnosed with peripheral arterial disease at the state of Critical Limb Ischemia and be unsuitable for bypass or revascularization. For information, call 1-888-853-4656 or go online to