Charles Krupa, Associated Press
Red Sox left fielder Jason Bay holds up his glove after catching a fly ball Friday against the Athletics.

BOSTON — Jason Bay made a smashing debut with Boston, tripling and scoring the winning run in the 12th inning Friday night as the Red Sox began the post-Manny Ramirez era with a 2-1 win over Oakland.

Bay was obtained from Pittsburgh on Thursday in the three-team deal that sent Ramirez to the Los Angeles Dodgers.

He failed to put the ball in play in his first five at-bats — two walks, a hit by pitch and two strikeouts — before he came up with two outs in the 12th against Alan Embree (1-4). He hit the ball high off wall in left and slid into third with a triple. J.D. Drew was walked intentionally.

Jed Lowrie, who had left the bases loaded in the 10th, hit a soft bouncer past the mound. Shortstop Bobby Crosby grabbed it and threw to first, but Lowrie beat the throw, scoring Bay.

Mike Timlin (4-3) got the win. He was the last of five Boston pitchers who allowed one run in 5 2-3 innings in relief of Tim Wakefield. It was just the second win in seven games for Boston.

Oakland is 2-13 in its last 15 games.

Jack Cust had tied the game 1-1 in the eighth with his 20th homer. Brad Ziegler extended his record shutout streak to start a career to 32 innings by blanking the Red Sox in the eighth and ninth.

ANGELS 1, YANKEES 0: At New York, Torii Hunter hit an RBI single off Mariano Rivera in the ninth, and Ervin Santana pitched eight stellar innings as Los Angeles won its fifth straight.

Rivera gave up a run for the third straight time when no save was involved, and fourth in the last six. Rivera is 26-of-26 in save chances.

After walking Mark Teixeira to start the inning, Rivera (4-4) gave up a single to Vladimir Guerrero to put runners at the corners before Hunter lined a single up the middle to score pinch-runner Reggie Willits.

The Angels began the day 12 1/2 games ahead in the West, their largest lead in club history. They are 12-2 since the All-Star break.

Los Angeles is 7-1 on its current road trip through Baltimore, Boston and New York.

New York lost for the fifth time in six games.

Santana (12-5) struck out eight. Francisco Rodriguez pitched a perfect ninth for his major league-leading 45th save.

Sidney Ponson allowed two hits in seven scoreless innings, his best start since joining the Yankees in June.

RAYS 5, TIGERS 2: At St. Petersburg, Fla., Carlos Pena and Evan Longoria hit solo homers and Tampa Bay's bullpen limited Detroit to one hit over the last 4 1/3 innings.

Grant Balfour (3-1) struck out three of the four batters he faced in relief of All-Star Scott Kazmir to get the victory. The right-hander, who began the season in the minors, lowered his ERA to 1.20 with four runs allowed and 45 strikeouts in 30 innings.

Pena's homer off Zach Miner (5-4) snapped a 2-2 tie in the sixth, was his fourth in eight games and briefly lifted him into a tie with Longoria for the team lead with 19.

Longoria, leading all major league rookies in home runs, hit No. 20 off Joel Zumaya to make it 5-2 in the seventh.

Troy Percival worked the ninth to finish the four-hitter, moving ahead of Randy Myers for sole possession of eighth place on the career saves list with 348.

Kazmir allowed two runs and three hits, and tied a career high with six walks in 4 2-3 innings.

TWINS 4, INDIANS 1: At Minneapolis, Joe Mauer's two-run homer in the seventh spoiled another strong start by Jeremy Sowers against Minnesota.

Mauer's seventh homer broke a 1-1 tie and Brendan Harris added an RBI double to back Nick Blackburn (8-6), who gave up one run and six hits in seven innings as Minnesota won for the sixth time in seven games.

For the second straight start against Minnesota, Sowers (1-6) took a perfect game into the sixth inning before Harris spoiled it with a leadoff double.

After Mauer's homer put the Twins ahead 3-1, Harris doubled home Randy Ruiz to chase Sowers, who gave up four runs and six hits in 6 2-3 innings.

Joe Nathan pitched the ninth for his 30th save.

Cleveland's Kelly Shoppach went 2-for-4 in his first game since tying a major league record with five extra-base hits — three doubles and two homers — in a 13-inning loss to Detroit on Wednesday.

WHITE SOX 4, ROYALS 2: At Kansas City, Mo., Ken Griffey Jr. drove in two runs in his debut with Chicago and Javier Vazquez won for the first time in seven starts.

The White Sox sent two players to Cincinnati for Griffey, a 38-year-old slugger who's battled injuries and struggled most of this season. Batting seventh for the first time since his rookie season in 1989 — he hit third for the Reds — Griffey fought off a tough pitch from Luke Hochevar (6-9) with two strikes, then lined a two-out single up the middle for the game's first run.

Griffey came up with two outs and runners on the corners in the sixth, and fisted a ball between first and second for a single that put Chicago up 2-0. He advanced on Nick Swisher's run-scoring infield hit, and scored on Juan Uribe's single to make it 4-0.

Griffey went 2-for-3 in his first AL game since 1999.

Vazquez (8-9) allowed two runs and five hits over six innings, winning for the first time since June 17 against Pittsburgh. Bobby Jenks pitched the ninth for his 22nd save.

ORIOLES 10, MARINERS 5: At Seattle, Garrett Olson threw eight scoreless innings before running into trouble in the ninth and the Baltimore Orioles scored six early runs off Jarrod Washburn in a victory over the Seattle Mariners.

Olson was working on an eight-hitter before the Mariners chased him during a five-run ninth inning. He worked 8 1-3 innings, and was charged with three runs and 11 hits.

RANGERS 9, BLUE JAYS 8: At Arlington, Texas, David Murphy's two-run single with one out in the bottom of the ninth capped Texas' three-run rally.

Pinch-hitter Jarrod Saltalamacchia drew a one-out walk from B.J. Ryan (2-4), and Michael Young followed with single.

Brandon Boggs, who entered the game when Josh Hamilton left with dizziness after the sixth inning, doubled to score Saltalamacchia.

Ryan, who blew his third save in 23 chances, intentionally walked Marlon Byrd to load the bases.

Murphy, who drove in four runs, hit a grounder just past a diving Scott Rolen at third to bring in the tying and winning runs.

C.J. Wilson (2-2) picked up the win despite allowing two runs in the ninth.

Adam Lind gave Toronto a 7-6 lead in the top of the ninth with a one-out triple, and he scored on Kevin Mench's RBI groundout.

National League

PIRATES 3, CUBS 0: At Chicago, Jeff Karstens threw six innings in his Pittsburgh debut, and the Pirates snapped Chicago's five-game winning streak with a 3-0 victory Friday.

Karstens (1-0), acquired last week for outfielder Xavier Nady, was one of three newcomers who led the Pirates. Andy LaRoche, obtained in the Manny Ramirez deal, singled and scored a run.

Right fielder Brandon Moss, who came from Boston in the trade for Jason Bay, started one of Pittsburgh's four double plays.

Jason Michaels had an RBI single in a two-run second, then hit a solo homer off Jason Marquis (6-7) in the sixth.

Jack Wilson added three hits and drove in the Pirates' other run.

Karstens gave up five hits in his 10th career start. Denny Bautista, Sean Burnett and John Grabow combined for three hitless innings of relief. Grabow got his first save of the season.

BREWERS 9, BRAVES 0: At Atlanta, Jeff Suppan pitched seven scoreless innings, and Mike Cameron and Prince Fielder hit third-inning home runs as Milwaukee snapped a five-game losing streak.

The Brewers opened a six-game trip with their eighth straight road victory after losing five in a row at home, including four to the Cubs.

Suppan (6-7) gave up five hits with three walks and one strikeout. Brian Shouse and Guillermo Mota each pitched an inning to complete the Brewers' fifth shutout.

The Braves, who have lost six of seven, again were without catcher Brian McCann, who missed his fifth straight game while recovering from a slight concussion. He was given medical clearance before the game for use as a pinch-hitter.

The Brewers scored six runs in the first three innings against Chuck James (2-4), who recalled from Triple-A Richmond for the start.

ROCKIES 5, MARLINS 2: At Miami, Ubaldo Jimenez allowed two hits in seven shutout innings to win his fourth straight start for Colorado. The right-hander struck out 10 and kept the Marlins hitless until Dan Uggla's leadoff single in the fifth. He walked three and hit a batter.

Manny Corpas pitched a scoreless eighth for Colorado, but Josh Willingham had an RBI single off Taylor Buchholz in the ninth. Buchholz was replaced Brian Fuentes, who gave up a sacrifice fly to Mike Jacobs between a strikeout and a popup for his 19th save.

Jimenez (8-9) increased his shutout streak to 13 innings. He has allowed one run in his last three starts.

Chris Iannetta and Brad Hawpe hit two-run singles for the Rockies. Hawpe had three of Colorado's 13 hits.

Chris Volstad (2-2), a 21-year-old rookie, allowed four earned runs and eight hits in five innings.

NATIONALS 5, REDS 2: At Washington, Odalis Perez pitched into the eighth inning to earn his first home win and Washington ended a nine-game losing streak.

It was Cincinnati's first game since it traded outfielder Ken Griffey Jr. to the Chicago White Sox on Thursday. Reliever Nick Masset, one of two players acquired by the Reds in the deal, allowed one hit in three scoreless innings.

Perez (4-8) won for the fourth time in 20 starts. He allowed one run and three hits over 7 1-3 innings in his longest start since he pitched eight innings in August 2005.

Homer Bailey (0-5) lasted two innings for Cincinnati, allowing five runs and seven hits.

Jesus Flores hit a two-run single in the first, and Washington added three in the second.

ASTROS 7, METS 3: At Houston, pinch-hitter Mark Loretta hit a tie-breaking grand slam off Aaron Heilman in the eighth for Houston.

Kazuo Matsui, Brandon Backe and Carlos Lee had solo homers, all leading off innings against Pedro Martinez, who made his first start since July 12, allowing five hits with five strikeouts in five innings.

Doug Brocail (5-5) got the final two outs of the eighth and Jose Valverde worked the ninth as the Astros won for the fifth time in seven games.

It was Loretta's second career grand slam.

The Mets loaded the bases with no outs in the seventh but didn't score as three different pitchers each got an out.

Miguel Tejada led off the eighth with a single against Heilman (1-5) and Lance Berkman followed with a ground-rule double to center. After an intentional walk and a groundout, Loretta hit his second pinch-hit homer this season.

GIANTS 3, PADRES 2: At San Diego, Pinch-hitter Eugenio Velez doubled off the wall in right field in the 10th inning to drive in the go-ahead run. Velez drove a 2-2 pitch off closer Trevor Hoffman (1-6) to score Emmanuel Burriss, who blooped a single to center.

CARDINALS 6, PHILLIES 3: At St. Louis, Ryan Ludwick homered twice and had four hits, and Joe Mather added a three-run shot for St. Louis.

Kyle Lohse cruised through five innings to help end his former team's five-game winning streak, and Jason Isringhausen earned his 12th save and first since May 5.

Ludwick homered off Cole Hamels (9-7) with two outs in the fifth and led off the eighth with a drive off Ryan Madson. It was his third multihomer game this season and fifth in his career.

Lohse (13-3) gave up his first hit with two outs in the fifth to Hamels. He gave up three runs in 5 1-3 innings, the second consecutive game he failed to get through the sixth.

The Cardinals scored four runs in the third off Hamels, who gave up four earned runs and eight hits in six innings.