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Tony Dejak, Associated Press
Cy Young winners Greg Maddux of San Diego and C.C. Sabathia of Cleveland squared off Sunday.

CLEVELAND — C.C. Sabathia outpitched Greg Maddux in a matchup of Cy Young winners, and the Cleveland Indians defeated the San Diego Padres 7-3 on Sunday.

Ben Francisco hit a three-run homer and Grady Sizemore a solo shot, his ninth homer in 16 games, as Cleveland took two of three in the interleague series.

Coming off a five-hitter against Minnesota on Tuesday, Sabathia (5-8) struck out 10 and allowed three runs and six hits over eight innings. His 14th game of double-digit strikeouts helped him past Charles Nagy for fifth place in Indians history with 1,239.

Maddux (3-5) fell to 0-2 in seven starts since May 10, when he became the ninth pitcher to win 350 games. The 42-year-old didn't issue a walk for the seventh time in 15 starts this season, but wasn't as sharp as usual. The four-time NL Cy Young winner hit a batter, threw a wild pitch, and even made an uncharacteristic error that led to three unearned runs.

YANKEES 13, ASTROS 0: At Houston, Chien-Ming Wang pitched five scoreless innings before spraining his right foot running the bases, and Alex Rodriguez hit a three-run homer in New York's rout of Houston. Wang (8-2) pulled up as he rounded third on Derek Jeter's two-run single during the Yankees' eight-run sixth inning. He hopped the rest of the way home and pointed to his right foot after scoring. A trainer rushed from the dugout to check on him and Wang was helped off the field.

RED SOX 9, REDS 0: At Cincinnati, Coco Crisp kept Boston's depleted lineup rolling by driving in four runs, and Jacoby Ellsbury homered and stole two more bases for a Red Sox rookie record in a victory over the Reds. The Red Sox hit four homers in their most lopsided victory of the season.

ROCKIES 5, WHITE SOX 3: At Chicago, Brad Hawpe hit a go-ahead home run, Aaron Cook earned his career-high 10th win and Colorado hung on to beat Chicago.

CUBS 7, BLUE JAYS 4: At Toronto, Ted Lilly allowed one hit over six scoreless innings, Derrek Lee drove in three runs and Aramis Ramirez homered for the Cubs. Lilly (7-5) won for the sixth time in seven decisions dating to May 3 and has a 3.81 ERA over that span. He struggled with his control but kept wiggling out of jams.

RANGERS 8-2, METS 7-4: At New York, Pedro Martinez pitched six sharp innings, pinch-hitter Robinson Cancel got his first major league hit in nearly nine years and the Mets salvaged a split of a doubleheader. Kevin Millwood (5-3) held the Mets to five hits over six innings to earn his first road win since last Father's Day in the first game.

TIGERS 5, DODGERS 4: At Detroit, Nate Robertson pitched six shutout innings, Marcus Thames and Brandon Inge hit back-to-back homers and Detroit won its sixth straight.

ANGELS 2, BRAVES 0: At Anaheim, Casey Kotchman homered, Joe Saunders pitched seven scoreless innings and Los Angeles avoided a sweep with a win over Atlanta.

MARLINS 9, RAYS 3: At St. Petersburg, Fla., Ricky Nolasco came within one out of the first complete game of his career, and Mike Jacobs and Wes Helms hit three-run homers Sunday to power Florida.

BREWERS 4, TWINS 2: At Milwaukee, Mike Cameron hit a two-run homer, Seth McClung scattered four hits and the Brewers snapped a six-game losing streak in interleague play dating to last season.

PIRATES 5, ORIOLES 4 (10): At Baltimore, Adam LaRoche singled in the tiebreaking run off George Sherrill in the 10th inning, and the Pirates beat Baltimore to end a run of seven straight interleague defeats.

ATHLETICS 5, GIANTS 3: At San Francisco, Eric Chavez had three hits and two RBIs to help Oakland complete its second consecutive sweep of San Francisco. Dana Eveland (5-5) gave up a run and six hits in 6 2/3 innings for the A's, who have won six straight over the Giants and four of five overall.

ROYALS 8, DIAMONDBACKS 3: At Phoenix, David DeJesus hit his first career grand slam and had a career-high five RBIs, helping the Royals win for the second time in three games against Arizona.

NATIONALS 6, MARINERS 2: At Seattle, rookie Kory Casto's pinch-hit, three-run homer off the foul pole broke an eighth inning tie and led Washington past Seattle.

National League

CARDINALS 7, PHILLIES 6 (10): At St. Louis, Rick Ankiel scored from second on the Philadelphia Phillies' second error at first base in the 10th inning, giving St. Louis the win over Philadelphia. The game was marred by a potentially serious injury to Cardinals catcher Yadier Molina in the ninth. Molina was removed on a stretcher and wearing a neck brace after getting run over on a tag play in the top of the inning. Molina was taken to a hospital for evaluation of neck and back pain.