Kathy Willens, Associated Press
Orioles' Adam Jones scores when Yankee catcher Jose Molina loses the ball.

NEW YORK — Just when the slumping New York Yankees got Alex Rodriguez back, Derek Jeter went down with an injury that nearly led to a brawl with Baltimore.

Adam Jones hit a three-run double during Baltimore's seven-run first inning against Mike Mussina (6-4), and the Orioles routed New York 12-2 Tuesday night in a testy game that included a late homer by A-Rod in his return from the disabled list.

The Orioles took advantage of a two-out throwing error by Jeter in the first to build a big cushion for Daniel Cabrera (5-1), who handed the Yankees (20-25) their fourth straight loss and sixth in seven games.

American League

ANGELS 3, BLUE JAYS 1: At Toronto, John Lackey won for the first time since Sept. 28, pitching seven strong innings to help the Angels get a rare victory in Toronto.

Making his second start of the year after returning from a strained triceps, Lackey (1-0) gave up a leadoff homer to Toronto's Brad Wilkerson in the first, then blanked the Blue Jays the rest of the way.

Francisco Rodriguez loaded the bases with three straight walks in the ninth, but held on to record his major-league leading 18th save. TIGERS 12, MARINERS 8: At Detroit, Justin Verlander struck out a season-high seven and Edgar Renteria hit one of Detroit's four homers and matched a career high with five RBIs in the Tigers' victory over Seattle. Curtis Granderson, Magglio Ordonez and Carlos Guillen also homered for the Tigers, who had lost six of seven.

RAYS 3, ATHLETICS 2: At Oakland, Calif., Scott Kazmir scraped out another impressive win thanks to a costly error by Oakland.

Left fielder Emil Brown tried to make a sliding catch on Dioner Navarro's sinking liner in the eighth inning and the ball got past him for a three-run error, sending the Rays to the win. RED SOX 2, ROYALS 1: At Boston, rookie Justin Masterson pitched 6 1/3 strong innings one day after Jon Lester's no-hitter against Kansas City and the Red Sox silenced the Royals bats again.

The 23-year-old Masterson (1-0) allowed one run on three hits in his second major league start. Jonathan Papelbon ended a bases-loaded threat in the eighth by striking out Billy Butler and pitched a perfect ninth — with two more strikeouts — for his 13th save in 15 opportunities. TWINS 11, RANGERS 4: At Minneapolis, Glen Perkins pitched six scoreless innings for his first major league win.

The Rangers lost their third in a row after Minnesota roughed up Texas starter Doug Mathis for nine runs in 2 1/3 innings. Mathis made his first major-league start since the Rangers purchased his contract from Triple-A Oklahoma on May 11 to replace the injured Kevin Millwood.

WHITE SOX 4, INDIANS 1: At Chicago, Jose Contreras outpitched C.C. Sabathia, and Jim Thome and Carlos Quentin hit solo homers to lift the White Sox for their season-high sixth straight win.

It's the White Sox's longest streak since they won nine in a row from June 15-24, 2006.

National League

MARLINS 3, D-BACKS 2: At Miami, Dan Uggla hit his 14th home run and Kevin Gregg escaped a bases-loaded jam in the eighth inning to help the Marlins take the opening game in a series between division leaders, beating Arizona 3-2 on Tuesday night.

BRAVES 6, METS 1, 1ST GAME: At Atlanta, Tom Glavine retired his last 17 batters during his first post-New York appearance against the Mets and led the Atlanta Braves to another home win in the opener of a day-night doubleheader.

The 42-year-old left-hander allowed only three hits and a walk — all in the first. Glavine (2-1) left after six innings, and Will Ohman, Blaine Boyer and Manny Acosta finished for the Braves.

BRAVES 6, METS 2, 2ND GAME: At Atlanta, Jorge Campillo pitched six scoreless innings for his first major league win, leading to the win and the sweep of their doubleheader with the Mets.

PHILLIES 1, NATIONALS 0: At Washington, Greg Dobbs' RBI pinch-hit single in the ninth inning gave the Philadelphia Phillies the victory.

Dobbs picked up the game-winning RBI as a pinch hitter for reliever Tom Gordon. Dobbs has 10 pinch hits and nine RBIs in 22 at-bats this season. BREWERS 7, PIRATES 2: At Pittsburgh, Manny Parra pitched 5 2/3 scoreless innings, and Mike Cameron and Corey Hart homered to help the Milwaukee Brewers snap a five-game losing streak.

Parra (2-2) won for the first time since beating San Francisco on April 5, his first start of the season. ASTROS 4, CUBS 2: At Houston, Hunter Pence hit a grand slam to lead the Astros .

A day after snapping a career-high 16-game hitting streak with an 0-for-4 night, Pence had three hits, including a shot to the first row in right field in the fourth inning.

GIANTS 6, ROCKIES 5: At Denver, Tim Lincecum pitched six effective innings, Rich Aurilia had three hits, including a solo homer, and San Francisco snapped a season-high six-game skid.

PADRES 3, CARDINALS 2: San Diego, Kevin Kouzmanoff hit a three-run homer in the sixth inning, a rare clutch hit for San Diego that carried the Padres to the win over the Cardinals but came too late to give Greg Maddux the victory.

DODGERS 4, REDS 1: At Los Angeles, Chad Billingsley pitched seven scoreless innings and singled home a run, leading the Dodgers and sending the Reds to their eighth straight loss at Chavez Ravine.