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Matthias Schrader, Associated Press
Wolfgang Ischinger, right, Chairman of the Munich Security Conference welcomes US Secretary of State Hillary Rodham Clinton, center, and U.S. Defense Secretary Leon Panetta at the Security Conference on Saturday, Feb. 4, 2012 in Munich, southern Germany. Politicians and military representatives will join for the 48. Munich Security conference from Friday, Feb. 3 until Sunday, Feb. 5, 2012.

MUNICH — The Obama administration on Saturday called for stepped up U.S.-European cooperation to isolate tyrannies like the Assad regime in Syria, promote democracy in the Arab World and beyond and repair damage from the global financial crisis.

And, as America shifts its primary strategic focus to Asia and reduces its military presence in Europe, President Barack Obama's top two national security aides — attending an international security conference here together in a demonstration of Washington's resolve — reassured the continent that it remains deeply relevant to U.S. interests as well as its partner of "first resort" in dealing with global hotspots.

U.S. Secretary of State Hillary Rodham Clinton said Americans and Europeans must send a clear and common message to tyrants that they must respect the rights of their people. She spoke as violence flared anew in Syria ahead of an expected vote on a U.N. Security Council resolution on the matter later Saturday.

"As a tyrant in Damascus brutalizes his own people, America and Europe stand shoulder to shoulder," she said, referring to Syrian President Bashar Assad.

"We are united, alongside the Arab League, in demanding an end to the bloodshed and a democratic future for Syria. And we are hopeful that at 10 a.m. Eastern Standard Time in New York the Security Council will express the will of the international community," she said.

Clinton said, "Wherever tyrants deny the legitimate demands of their own people, we need to work together to send them a clear message: You cannot hold back the future at the point of a gun."

While promoting democracy, she warned that Europe could not ignore backsliding in its own backyard, decrying limits being placed on press and religious freedoms. She did not identify trouble spots by name but was referring to Russia, Belarus and Hungary.

"It is not credible to preach democracy elsewhere unless we also protect it within our community," she said. "The trappings of democracy are not enough."

Clinton said she had no doubt that Europe would overcome its economic woes. But she said it was imperative for a common agenda and enhanced cooperation to reinforce recoveries on both sides of the Atlantic.

"We are confident that Europe has the will and the means to cut its debt, build the necessary firewalls, create growth, and restore liquidity and market confidence," she said. But, she added: "As Europe emerges from crisis, we have to work harder to reinforce each other's recoveries. As deep as our economic relationship is, it has not yet lived up to its potential."

To boost the recovery, she said the United States and Europe need to team up to fight unfair trade practices.

Meanwhile, U.S. Defense Secretary Leon Panetta said Europe is America's security partner of choice for military operations and diplomacy around the world. He said Europe will continue to be a central U.S. defense interest, even as the administration withdraws two of the four Army brigades stationed on the continent.

In his remarks to the conference, Panetta emphasized the positive. He noted that the U.S. is building a missile defense system in Europe, including a radar installation in Turkey and missiles to be stationed in Romania and Poland. He said four U.S. ships capable of shooting down missiles will be stationed at Rota, Spain.

And he said that while two Army brigades will leave Europe, that will be partly offset by a new arrangement in which smaller Army units will rotate to the continent for temporary training assignments. This was announced in January as part of a new U.S. defense strategy.

These changes, he said, amount to a U.S. "vote of confidence" in the future of NATO.

The Obama administration has sought to limit the diplomatic fallout from its decision to pull the Army brigades out of Europe — a move in line with an overall shrinking of the Army from 570,000 soldiers to 490,000. One brigade is scheduled to pull out of Europe in 2013 and another in 2014.

Missile defense will become a central feature of the U.S. military presence in Europe. Officials in recent days confirmed that the missile defense system's headquarters will be at Ramstein air base in Germany.

Panetta came to Munich after two days of consultations with his NATO counterparts in Brussels. He reviewed for them the new U.S. defense strategy and plans to reduce planned defense spending by nearly $490 billion over 10 years.

Associated Press National Security writer Robert Burns contributed to this report.