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Charles Dharapak, Associated Press
Republican presidential candidate, former Massachusetts Gov. Mitt Romney, campaigns at the University of South Carolina Aiken, in Aiken, S.C., Friday, Jan. 13, 2012.

WASHINGTON — South Carolina may be fertile ground for attacks on Mitt Romney's corporate takeover record.

The state has suffered a long string of shuttered workplaces. Its unemployment rate of nearly 10 percent is one highest in the nation. And its Republican electorate has a disproportionate number of blue-collar workers and noncollege graduates.

That combination could make it a good test of efforts to paint the GOP presidential front-runner as a heartless corporate raider from his time at Bain Capital.

Newt Gingrich and Rick Perry have made just such claims as they struggle to keep their presidential hopes alive.

South Carolina's Jan. 21 primary may mark the last real chance to stop Romney's drive to the nomination.