Richard Drew, File, Associated Press
FILE - In this Nov. 21, 2011 file photo, traders Richard Cohen, center, and Lewis Vande-Pallen, right, work on the floor of the New York Stock Exchange. Stocks took another pounding Friday, Nov. 25, 2001 after Italy's borrowing rates ratcheted higher following a pair of hugely disappointing auctions from the eurozone's third-largest economy.

NEW YORK — U.S. stock futures are falling, with major indexes poised to end their worst week since September.

Worries about Europe's debt crisis flared up again on Friday, after Italy had to pay 7.8 percent to borrow for two years at a debt auction.

Less than two hours before the opening bell, Dow Jones industrial average futures are down 64 points, or 0.57 percent, to 11,170. The Dow has already lost 4.6 percent this week, putting the average on track for its worst week since September.

S&P 500 index futures are down 6, or 0.6 percent, to 1,153. Nasdaq 100 futures are down 12, or 0.6 percent, to 2,149.

Trading will end at 1 p.m. Eastern time. U.S. markets were closed on Thursday for the Thanksgiving holiday.