Kevin Lamarque, Pool, Associated Press
U.S. Secretary of State Hillary Clinton answers a question during a talk in Islamabad, Pakistan, Friday, Oct. 21, 2011. The Obama administration on Friday intensified pressure on Pakistan to do more to crack down Islamist militants destabilizing Afghanistan, as U.S. Secretary of State Hillary Rodham Clinton delivered a tough public message that extremists have been able to operate in and from Pakistan for too long.

ISLAMABAD — Washington's troubled relationship with Pakistan has triggered plenty of heartburn for U.S. officials, but rarely sidesplitting laughter.

That changed Friday when Secretary of State Hillary Rodham Clinton erupted in amusement during a town hall meeting in Islamabad when a participant described the U.S. as Pakistan's impossible to please mother-in-law.

"We all know that the whole of Pakistan is facing the brunt of whatever is happening and trying to cooperate with the U.S., and somehow the U.S. is like a mother-in-law which is just not satisfied with us," said a woman who identified herself as Shamama and elicited a round of applause from the crowd.

"We are trying to please you, and every time you come and visit us you have a new idea and tell us, 'You are not doing enough and need to work harder,'" said Shamama, who works for a women's group in northwest Khyber Pakhtunkhwa province near the Afghan border.

Laughing at length, Clinton said she could personally relate to the woman's perspective because she too was a mother-in-law. The secretary of state's daughter, Chelsea, married an investment banker this summer in New York.

"I think that's a great analogy I have never heard before," said Clinton. "Now that I am a mother-in-law, I totally understand what you're saying and hope to do better privately and publicly."

The U.S. and Pakistan have long had a troubled relationship that got even worse this year following the arrest of a CIA contractor, the covert raid that killed Osama bin Laden in a Pakistani garrison town and, most recently, allegations that Pakistan's spy agency has supported militants attacking American targets in Afghanistan. Pakistan has denied the claim.

The U.S. has given Pakistan billions of dollars in military and civilian aid in an attempt to elicit greater cooperation on the Afghan war, but has come away frustrated.

Pakistani officials and ordinary citizens have also soured on the relationship, perceiving the U.S. as only interested in buying the country's anti-terror cooperation, rather than investing in a long-term partnership.

Clinton's two-day visit to Pakistan, alongside CIA chief David Petraeus and Chairman of the Joint Chiefs of Staff Gen. Martin Dempsey, was focused both on stepping up pressure on Islamabad and preventing the relationship from totally unraveling.

"I personally believe this relationship is critical, important to us both, and therefore we cannot give it up," said Clinton. "Once a mother-in-law always a mother-in-law, but perhaps mothers-in-law can learn new ways also."