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Gail Burton, Associated Press
Baltimore Orioles pitcher Jeremy Guthrie delivers against the Cleveland Indians during the fourth inning of a baseball game, Thursday, July 14, 2011, in Baltimore.

BALTIMORE — Asdrubal Cabrera and Carlos Santana homered, Justin Masterson struck out eight in six innings, and the Cleveland Indians beat Baltimore 8-4 Thursday night to extend the Orioles' losing streak to eight games.

The victory moved the Indians into first place in the AL Central, percentage points ahead of idle Detroit. Cleveland lost three straight before the All-Star break to fall out of first for the first time since June 28.

Cabrera and Santana connected in a three-run first inning against Jeremy Guthrie (3-13), giving the Indians the lead for good. Cleveland is 4-0 against Baltimore this season, outscoring the Orioles 28-11.

Masterson (8-6) gave up four runs and eight hits, improving to 3-0 in his last three starts.