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Matt Slocum, Associated Press
Philadelphia Phillies' Raul Ibanez, left, follows through after hitting an RBI-double off Houston Astros starting pitcher Wandy Rodriguez, not pictured, in the first inning of a baseball game, Saturday, April 2, 2011, in Philadelphia. At right is Houston's J.R. Towles.

PHILADELPHIA — Cliff Lee struck out 11 over seven impressive innings in his first game back with Philadelphia, five players had multiple hits and the Phillies beat the Houston Astros 9-4 Saturday night.

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A day after rallying against closer Brandon Lyon for a comeback win in the ninth, the Phillies roughed up starter Wandy Rodriguez.

The victory might be costly to the Phillies because center fielder Shane Victorino left with soreness in his left calf. There was no immediate word on the extent of his injury, but Victorino has twice been on the disabled list with calf strains.

The Phillies already are missing second baseman Chase Utley, closer Brad Lidge and outfielder Domonic Brown.

Lee (1-0) allowed three runs and four hits.