Mark Duncan, Associated Press
Boston's Manny Ramirez, right, is greeted by Jacoby Ellsbury after Ramirez belted a homer Monday.

CLEVELAND — Six months later, the Red Sox came back on the Indians again.

Manny Ramirez hit a two-run homer — No. 493 of his career — and Boston rallied for three runs in the ninth inning against closer Joe Borowski for a 6-4 win Monday night over Cleveland in a stunning rerun of last October's AL championship series.

Julio Lugo hit a leadoff double in the ninth off Borowski, snapping an 0-for-16 slump, and scored on Dustin Pedroia's sacrifice fly to tie it 4-all.

With the Indians shifted to the right, David Ortiz dropped a bloop single into left — his second hit. Ramirez then belted Borowski's first pitch into the left-field seats, a place he frequently visited with long balls while a member of the Indians.

The homer tied the long-haired hitting machine with Hall of Famer Lou Gehrig and Fred McGriff for 24th on the career list.

AMERICAN LEAGUE

YANKEES 8, RAYS 7: At St. Petersburg, Fla., Robinson Cano's pinch-hit homer snapped an eighth-inning tie, and Alex Rodriguez hit No. 521 to match Hall of Famers Ted Williams and Willie McCovey for 15th on the career list in New York's victory over Tampa Bay.

With shortstop Derek Jeter back in the lineup, Yankees starter Ian Kennedy cruised into the seventh inning with a 7-2 lead before he was hit on the right hip by Jason Bartlett's line drive, knocking him out of the game.

TIGERS 11, TWINS 9: At Detroit, Ivan Rodriguez tied it with a two-run triple in a six-run eighth inning, then scored the go-ahead run on Jacque Jones' sacrifice fly to lift the high-priced Tigers past Minnesota for their first win at home this season.

Rodriguez also homered in the seventh and the Tigers won for the first time in seven home games. They improved to 3-10 overall, still the worst record in baseball.

Detroit's much-hyped lineup finally came through, leading to a season high in runs, just when it seemed the team's miserable start was going to take another turn for the worse.

ORIOLES 4, BLUE JAYS 3: At Baltimore, Kevin Millar homered and drove in three runs to back a fine pitching performance by Matt Albers in Baltimore's victory over Toronto.

Adam Jones tied a career high with three hits for the Orioles, who won their sixth straight home game and broke a first-place tie with the Blue Jays in the AL East.

Obtained in the offseason trade that sent Miguel Tejada to Houston, Albers (2-0) allowed one run, five hits and a walk in five innings to earn his first AL win.

Jim Johnson pitched 2 1/3 innings of two-hit relief and George Sherrill earned his sixth save in six tries.

Alex Rios had a pinch-hit, two-run homer in the ninth — the first runs this season against Sherrill.

Dustin McGowan (0-1) gave up three runs and 10 hits in six innings.

ATHLETICS 2, WHITE SOX 1: At Chicago, Greg Smith outpitched Mark Buehrle for his first major league win, and Kurt Suzuki went 4-for-4 as Oakland won its eighth in 10 games.

The A's are 6-1 on their first road trip of the season and they improved to 9-5 overall for their best start through 14 games since opening 10-4 in 1992.

Making his second big league appearance, Smith (1-0) gave up one run and six hits over seven innings.

Huston Street got his fourth save in five chances with a shaky ninth.

Buehrle (1-1), who hadn't pitched in eight days because of a rainout and a decision to give him an extra day of rest, gave up nine hits in seven innings while his career mark against Oakland dropped to 3-10.

ANGELS 7, RANGERS 4: At Arlington, Texas, Ervin Santana rebounded from a three-run first to pitch seven strong innings, and Mike Napoli homered as Los Angeles handed Texas its fourth straight loss.

Santana (2-0) came in 1-4 with an 8.92 ERA against the Rangers on the road and quickly fell behind, allowing Hank Blalock's two-run homer and Michael Young's sacrifice fly in the first. But after loading the bases in the third, he retired 11 straight.

Francisco Rodriguez pitched a perfect ninth for his fourth save.

ROYALS 5, MARINERS 1: At Seattle, Zack Greinke pitched a five-hitter for his third career complete game, and the Kansas City Royals opened a seven-game road trip with a win over the Mariners.

Billy Butler and Miguel Olivo each hit their first homer of the season for Kansas City.

Greinke (3-0) joined teammate Brian Bannister with his third win, though his ERA climbed from 0.60 to 0.75. The right-hander was efficient, striking out four and inducing three double plays while facing only three batters more than the minimum.

NATIONAL LEAGUE

PIRATES 6, DODGERS 4: At Los Angeles, Nate McLouth extended his season-opening hitting streak to 13 games with a two-out, three-run homer off closer Takashi Saito in the ninth inning, and the Pirates stunned Dodgers for their fourth straight victory.

GIANTS 5, DIAMONDBACKS 4: At San Francisco, Randy Winn drove in two runs and Aaron Rowand, Ray Durham and Benji Molina also had RBIs to lead the Giants to the win over the hot Diamondbacks.

Conor Jackson homered and drove in three for the D-Backs.