Toronto's Aaron Hill congratulates Frank Thomas after his game-winning grand slam Sunday.

TORONTO — Frank Thomas broke a fifth-inning tie with his 11th career grand slam, Vernon Wells added a two-run homer and the Toronto Blue Jays beat the Boston Red Sox 7-4 Sunday to complete a three-game sweep of the World Series champions.

Boston went 3-4 on its opening three-nation trip to Tokyo, Oakland and Toronto, a journey of nearly 16,000 miles, and is last in the AL East for the first time since April 10, 2005.

Out since mid-March because of a strained lower back, Josh Beckett (0-1) was activated from the disabled list to face Roy Halladay (1-1). Beckett gave up five runs, three hits and four walks in 4 2-3 innings, striking out six.

Halladay allowed four runs and eight hits in eight innings. Jeremy Accardo pitched the ninth for his third save.

YANKEES 2, RAYS 0: At New York, Chien-Ming Wang (2-0) pitched four-hit ball into the seventh inning, Hideki Matsui hit a two-run homer in the fourth off James Shields (1-1) and Yankees manager Joe Girardi was back on the bench following an illness, Joba Chamberlain relieved with runners at the corners and no outs in the seventh, struck out Willy Aybar on three pitches and got Shawn Riggans on a liner that second baseman Robinson Cano caught with a backhand stab before doubling up Eric Hinske.

Hitting 101 mph on the stadium radar gun, Chamberlain tossed a perfect eighth to set up Mariano Rivera, who fanned two in a 1-2-3 ninth for his third save — a total he didn't reach last year until May 3.

ROYALS 3, TWINS 1: At Minneapolis, Brett Tomko (1-0) allowed six hits in five shutout innings, Alex Gordon hit a two-run single and scored after doubling in the seventh. Joakim Soria struck out the side in order in the ninth for his third save. Kansas City finished its opening trip to Detroit and Minnesota 4-2, its best start since 2004. The Royals had only three winning trips last season, none until May 11-20.

Boof Bonser (0-2) gave up three runs and eight hits in seven innings.

ORIOLES 3, MARINERS 2: At Baltimore, Luis Hernandez singled in the winning run with two outs in the ninth off Mark Lowe (0-1), who also threw a tying wild pitch. Nick Markakis led off the ninth with a double off Eric O'Flaherty and scored on a groundout by Aubrey Huff. Seattle, without injured closer J.J. Putz, wasted an outstanding performance by Felix Hernandez, who allowed five hits in eight shutout innings as a replacement for former-Oriole Erik Bedard, scratched Saturday because of an injured hip.

RANGERS 10, ANGELS 4: At Anaheim, Gerald Laird had four hits, homered twice and drove in a career-high six runs. Laird hit a three-run homer in the fourth off Jon Garland (1-1), his first RBIs of the season, then added an RBI single in the seventh against Darren O'Day and a two-run homer in the ninth off Jason Bulger.

Ben Broussard hit a two-run homer for Texas, which took two of three in the Angels' home-opening series.

Vicente Padilla (1-0) gave up four runs — three earned — and nine hits in seven innings, allowing solo homers by Garret Anderson and Torii Hunter.

INDIANS 2, ATHLETICS 1: At Oakland, Cliff Lee (1-0) gave up four hits and struck out four in 6 2-3 innings to win his first start of the season, retiring 10 of his last 12 batters as Cleveland stopped a three-game losing streak.

Joe Borowski pitched the ninth for his second save, following Rafael Perez and Rafael Betancourt and completing a four-hitter.

Asdrubal Cabrera hit an RBI groundout in the seventh off Joe Blanton (0-2), with first baseman Daric Barton bobbling the ball briefly as pinch-runner Jamey Carroll scored. Ryan Garko walked with the bases loaded after the A's intentionally walked Grady Sizemore.

WHITE SOX 13, TIGERS 2: At Detroit, Nick Swisher homered on the game's second pitch, Carlos Quentin had four RBIs and Chicago handed the Tigers their sixth straight loss. Despite the second-highest payroll in baseball, the Tigers, the only winless team in the majors, are off to their worst start since going 0-9 at the beginning 2003, when they lost an AL-record 119 games.

Mark Buehrle (1-0) rebounded from being tagged for seven runs on opening day, holding the Tigers to two runs and seven hits in seven innings.

Justin Verlander (0-1) allowed a career-high nine runs — four earned — in 5 2-3 innings. He gave up seven hits and walked three, striking out four.

National League

REDS 8, PHILLIES 2: At Cincinnati , Ken Griffey Jr. hit his 594th career homer Sunday, a two-run shot that powered Cincinnati over Philadelphia. Griffey's first homer of the season, a drive off Brett Myers (0-1), left him six shy of becoming the sixth player in major league history to reach 600 homers. He would join Barry Bonds, Hank Aaron, Babe Ruth, Willie Mays and Sammy Sosa. Jeff Keppinger homered and drove in three runs for the Reds, and Edinson Volquez (1-0) struck out eight in 5 1-3 innings.

BREWERS 7, GIANTS 0: At Milwaukee, Ben Sheets (1-0) struck out eight, walked none and pitched a five-hitter for his second career shutout, his first since a five-hitter against St. Louis on May 29, 2001. He retired his last 10 batters. Ryan Braun fell a triple short of the cycle, going 3-for-5 with three RBIs and Gabe Kapler homered for the second time in as many days as the Brewers scored in the second, third, fourth and fifth innings off Barry Zito (0-2), who allowed five runs — three earned — and eight hits in five innings. Zito has a 6.30 ERA.

DIAMONDBACKS 5, ROCKIES 2: At Denver, Mark Reynolds hit a two-run homer in the ninth off Manny Corpas and Stephen Drew hit a tiebreaking drive against Micah Bowie (0-1) leading off a three-run 10th as the Diamondbacks completed a three-game sweep against the team that beat Arizona 4-0 in last year's NL championship series.

Colorado, which lost its fifth straight, led 1-0 before Reynolds homered. Matt Holliday homered in the ninth off Brandon Lyon (1-1), who blew his second save chance.

Chad Qualls walked the first two batters in the 10th, then got his first save when Ryan Spilborghs grounded into double play and Troy Tulowitzki lined out.

BRAVES 3, METS 1: At Atlanta, John Smoltz (1-0) allowed two hits over five scoreless innings in his season debut to beat Johan Santana (1-1) as Atlanta completed a two-game sweep of the rain-shortened series. Santana gave up only one run in seven innings — Yunel Escobar doubled in Mark Kotsay in the third — and Mark Teixeira hit a two-run homer off Aaron Heilman in the eighth.

Ryan Church hit an RBI single with two outs in the ninth off Rafael Soriano, who completed a five-hitter and got his first save of the season when Teixeira made a diving stop of Brian Schneider's sharp grounder to first.

DODGERS 3, PADRES 2: Trevor Hoffman (0-2) allowed Chin-lung Hu's tiebreaking RBI single in the ninth inning. Baseball's career leader with 526 saves, also lost Tuesday when he blew a save against Houston and has a 12.27 ERA in four games. Jonathan Broxton (1-0) pitched 1 1-3 innings for the win, and Takashi Saito got three outs for his first save.

CUBS 3, ASTROS 2: At Chicago, Derrek Lee hit a tiebreaking homer against Oscar Villarreal (0-2) in the seventh, Lee's third homer of the season. He didn't hit his first homer last season until the 21st game and finished the season with only 22. Carlos Zambrano (1-0) struck out seven in seven innings, allowing two runs and seven hits with no walks, and Kerry Wood pitched a perfect ninth for his third save. Alfonso Soriano was 1-for-24 this season when homered off Brandon Backe for a 2-1 lead in the fifth. Miguel Tejada hit his first homer with Houston leading off the seventh.

CARDINALS 3, NATIONALS 0: At St. Louis, Kyle Lohse (1-0) allowed four hits in seven innings, Rick Ankiel homered and St. Louis completed a three-game sweep. Despite a major league-high nine players on the disabled list, the Cardinals have won five straight since losing on opening day and are 5-1 for the first time since winning seven of eight to start 2000. Jason Isringhausen pitched the ninth for his third save, helped by a leaping catch by Ankiel in center field on a Lastings Milledge drive. Rookie John Lannan (0-1) allowed two runs in 6 2/3 innings for the Nationals, who have lost four in a row after a 3-0 start.

PIRATES 9, MARLINS 2: At Miami, Ian Snell (1-0) struck out 10 in six innings, allowing two runs — one earned — and four hits. Xavier Nady homered, and Nate McLouth had three hits and scored three runs for Pittsburgh, which finished with 15 hits. Chris Gomez went 3-for-4. Rick VandenHurk (0-1) gave up four runs and six hits in 2 1/3 innings.