The drug DES, given to women to prevent miscarriage until it was shown to cause cancer in their daughters, may also cause cancer in their grand-daughters, U.S. government researchers said Friday.

They said tests on mice showed the drug's bad effects can linger for three generations."The data suggest transmission of susceptibility of genital tract cancers to subsequent generations," Retha Newbold of the National Institute of Environmental Health Sciences wrote in a report in the journal Carcinogenesis.