The Food and Drug Administration has granted permission to VaxGen Inc. for the nation's first large-scale trial for an AIDS prevention vaccine, The Wall Street Journal reported Wednesday.

Headed by virologist Donald Francis, who successfully battled the Ebola virus in the Sudan and smallpox in India, the three-year trial of Aidsvax will include 5,000 U.S. volunteers and 2,500 volunteers in Thailand.Tests in the United States were expected to begin this month, the Journal said, and in Thailand by the end of the year.