University of Utah researchers are seeking post-menopausal women to participate in clinical trials of estrogen and progesterone.

The hormone studies, part of a $50 million trial sponsored by Ayerst Laboratories at centers nationwide, is designed to study what combinations and doses of hormones are most effective for women after menopause.Many gynecologists believe that hormonal replacement will keep bones stronger and lessen the risk of coronary artery disease in older women.

Current drug therapy includes a 25- to 30-day course of of estrogen and 10 to 12 days of progesterone - a combination that causes about 70 percent of women to menstruate for many years after menopause.

To be elgible for the study, women must be 45 to 65 years old, not have had a hysterectomy and not have menstruated for at least 12 months. At the conclusion of the one-year drug trial, which will include seven visits to University Hospital, participants will receive $300.

For information, call nurse Tyrrel Boehme, at 581-4094.