The BYU Cougars surrendered a 15-point lead to lose to the San Francisco Dons, 99-87, in the Marriott Center on Saturday night.
The Dons outscored BYU by 60-39 in the second half, seemingly making every shot they took.
The loss will hurt BYU's tournament chances, after they lost on the road to San Diego on Thursday. This makes it only the fourth time that Dave Rose has suffered consecutive losses as BYU head coach.
BYU's shooting let them down, scoring 42 percent from the field and just 32 percent from beyond the arc. Brock Zylstra scored 18 points for the Cougars, but Tyler Haws and Brandon Davies have had better games for BYU. The latter only had three points in the second half.
Junior guard De'End Parker had 23 points off the bench for the Dons, playing a huge part in the comeback that gave USF the eventual victory.
This loss puts BYU at 18-8 for the season.