Can blood-pressure medicine boost sugar levels in blood?

Q: I take hydrochlorothiazide (HCTZ) and lisinopril to control high blood pressure. My doctor says I am pre-diabetic and encouraged me to consult a dietitian for advice on diet to prevent diabetes.

The nutritionist warned me that HCTZ could raise blood-sugar levels. If that is true, I'd really prefer some natural approaches to control both blood pressure and blood sugar. I don't want to take more medicine to treat a drug side effect. Any information you can provide will be appreciated.

A: The dietitian is correct that HCTZ can raise blood sugar. Don't stop this blood pressure medicine on your own, though. Ask your doctor about another type of blood-pressure medication. He has many other options he might prescribe.

With careful attention to your diet, you may be able to lower both your blood pressure and your blood sugar. We are sending you our brand-new book, "Favorite Foods From The People's Pharmacy." It has chapters describing scientific studies on using food to control blood pressure and type 2 diabetes, as well as a discussion of how to follow the DASH diet (Dietary Approaches to Stop Hypertension). The book is available online (www.peoplespharmacy.com).

Q: Have you ever heard of ibuprofen helping men with prostate problems? I am a runner and frequently use ibuprofen after a long run. I discovered that on the days that I took ibuprofen, I didn't have to get up at night to go to the bathroom.

When I have beer with the boys in the evening, I take ibuprofen afterward and don't have to get up to pee. Normally, I would be up and down a couple of times.

A: At first, we were skeptical that ibuprofen could have any benefit for benign prostate enlargement. Then we did a little digging. You may be on to something.

A double-blind study published in Urology (October 2008) included 80 men whose prostate problems interfered with nightly sleep. Half got Celebrex before bedtime, while the other half received a placebo. After a month, the men on Celebrex had fewer symptoms and half as many nightly trips to the bathroom.

Celebrex and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs). They should not be taken after drinking beer or other alcohol, since stomach irritation is more likely. We also would advise men to check with their doctors, as NSAIDs can raise blood pressure, cause stomach ulcers and interact with prescription drugs.