Aides said the Gingrich campaign had purchased a full-page newspaper ad in New Hampshire for Wednesday morning calling Romney a "Timid Massachusetts Moderate."
Romney, who finished second in Iowa in 2008 despite a costly effort, initially campaigned cautiously this time around.
But he barnstormed extensively across the state in the race's final days in pursuit of a first-place finish, running as a conservative businessman with the skills to fix the economy and as the challenger with the best chance to defeat Obama.
Santorum, Gingrich, Perry and Bachmann argued that Romney wasn't nearly conservative enough on the economy and social issues such as abortion. They vied for months to emerge as the alternative to the former Massachusetts governor.
Paul's libertarian-leaning views set him apart, and he hoped that might be enough to claim victory in a six-way race where no one broke away from the pack.
Unlike in a primary, in which voting occurs over hours, the 809 Iowa caucuses were meetings in which Republicans gathered for an evening of politics. Each presidential candidate was entitled to have a supporter deliver a speech on his or her behalf before straw ballots were taken.
Under party rules, caucus results have no control over the allocation of Iowa's 25 delegates to the Republican National Convention. The Associated Press uses the caucus outcome to calculate the number each candidate would win if his support remained unchanged in the pre-convention months.
The race in Iowa came to be defined by its unpredictability as the months rolled by and nationally televised candidate debates piled up.
Bachmann gained early momentum on the strength of a victory in a summertime straw poll and a feisty debate performance.
But she quickly faltered when Perry joined the race and overshadowed her as the 10-year governor of Texas with deep-pocketed supporters and an unbroken record of electoral success at home.
Perry's rise lasted only as long as a couple of debates including one where he memorably was unable to recall the third of three federal agencies he wanted to abolish.
Next up was Herman Cain, a black former businessman who improbably shot to the top of the polls in a party that draws its support chiefly from white voters. He suspended his candidacy a few weeks later, after a woman said she and he had carried on a long-term extra-marital affair.
Gingrich rode the next surge in the polls, a remarkable comeback for a man whose campaign had imploded earlier in 2011 when most of his aides quit in frustration. But his rise lasted only until a super PAC that supports Romney began attacking him on television.
Democrats watched carefully in a state that has swung between the two parties in recent presidential elections.
It was Iowa that launched Obama on the way to the White House four years ago when he won a convincing victory in the caucuses.
David Espo reported from Washington.
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The real news is that Gingrich is in 4th and Perry is in 5th. Paul and Santorum have no staying power.
The result:
Mitt Romney will be the 2012 Republican nominee.
We'll gladly take this W and then blitz the competition in New Hampshire.
Mitt 2012.
I hardly think 8 votes consitute a resounding win, more like a tie. If this had been an election and not a caucus there would be a recount ordered.
Maybe Jom Humtsman was the smart one to stay out of Iowa.