PHILADELPHIA — Eli Manning delivered the knockout blow after Michael Vick got knocked out of another game.
Manning threw four touchdown passes, including two to Victor Cruz, and the New York Giants beat the Philadelphia Eagles 29-16 Sunday.
Vick started despite suffering a concussion in last week's 35-31 loss at Atlanta. He left with a broken right hand in the fourth quarter after helping the Eagles overcome a 14-0 first-quarter deficit to take a 16-14 lead.
It's uncertain how long Vick will be out. He'll have a CT scan Monday.
"I don't know anything right now except my hand is broken," Vick said.
Vick wasn't happy with the hit, either. He completed a 23-yard pass to Jeremy Maclin before taking a hard shot from Chris Canty.
"I felt I got hit late. No flag," Vick said. "At some point something catastrophic is gonna happen. Not to blame the refs, but more precautions should be taken. I'm on the ground all the time in the pocket."
Without their Pro Bowl quarterback, the Eagles (1-2) hardly look like the "Dream Team" that entered the season with Super Bowl or bust expectations.
Manning threw a pair of TD passes in the fourth quarter to rally New York. The Giants (2-1) have won two in a row and snapped a six-game losing streak against their division rivals.
"It's always good to beat those guys, especially here," Manning said. "They have good players and we new we had to come in with the same game plan as last year and just finish it this time."
In their previous meeting at the Meadowlands last December, the Eagles rallied from a 21-point deficit with 8:17 left, and won 38-31 on DeSean Jackson's 65-yard punt return for a touchdown on the last play.
The teams traded a lot of trash talk in the offseason and during the week. The Giants backed it up.
"I think I responded today," Giants safety Antrel Rolle said. "I'm not scared of anyone on the field. I thing it's more mental than physical. They tried to get in my head sticking their hands in my face, blocking me after the play, but if they want to fight, I'll fight anyone, but in between the lines, I'm too smart to get thrown out of the game."
Manning threw for 254 yards, and Ahmad Bradshaw ran for 86 and had 53 more receiving, including a TD. Filling in because Mario Manningham and Domenik Hixon are out, Cruz had three catches for 110 yards and his first two career scores.
Aaron Ross, who was benched in the second half of New York's win over St. Louis last Monday, had two interceptions that led to 14 points.
LeSean McCoy had 128 yards rushing and one TD for Philadelphia, which has blown two fourth-quarter leads in consecutive games.
After McCoy was stopped for a 3-yard loss by Michael Boley on fourth-and-1 from the Giants 43, Manning drove New York in for the go-ahead score. He tossed a 28-yard TD pass to a well-covered Cruz to put the Giants up 20-16. Jacobs ran in for the 2-point conversion to make it 22-16.
Cruz outfought Nnamdi Asomugha and Jarrad Page to make the catch near the goal line and fell into the end zone, losing the ball after he crossed.
"It means the world to me because a lot of people were saying our receivers were down and who would step up and I was happy to be that guy that stepped up to help my team," Cruz said.
Mike Kafka replaced Vick on the ensuing possession and Ross intercepted his first pass. Manning connected with Bradshaw for an 18-yard TD pass to put the game away.
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