CAIRO — Thousands of state workers and impoverished Egyptians went on strike Wednesday after weeks of anti-government protests cast a spotlight on corruption and the wealth amassed by those in power in a country where almost half the people live near the poverty line.

The protests calling for President Hosni Mubarak's ouster have been spreading since Tuesday outside of Cairo's Tahrir Square, where they have been concentrated for the past week. On Wednesday, demonstrators also gathered at parliament, the Cabinet and the Health Ministry buildings, all a few blocks from the square. Prime Minister Ahmed Shafiq was working out of the Civil Aviation Ministry on the other side of the city because his office was blocked by protesters.

For the first time, protesters were forcefully urging labor strikes despite a warning by Vice President Omar Suleiman that calls for civil disobedience are "very dangerous for society and we can't put up with this at all." His warnings Tuesday were taken by protesters as a thinly veiled threat of another crackdown.

Strikes erupted in a breadth of sectors — among railway and bus workers, state electricity staff and service technicians at the Suez Canal, in factories manufacturing textiles, steel and beverages and at least one hospital.

"They were motivated to strike when they heard about how many billions the Mubarak family was worth," said Kamal Abbas, a labor leader. "They said: 'How much longer should we be silent?'"

Egyptians have been infuriated by newspaper reports that the Mubarak family has amassed billions, and perhaps tens of billions of dollars in wealth while, according to the World Bank, about 40 percent of the country's 80 million people live below or near the poverty line of $2 a day. The family's true net worth is not known.

"O Mubarak, tell us where you get $70 billion dollars," dozens of protesters chanted in front of the Health Ministry.

Growing labor unrest is adding a new dimension to the pressures for Mubarak to step down. The protesters filling streets of Cairo and other cities for the past 16 days have already posed the greatest challenge to the president's authoritarian rule since he came to power 30 years ago. They have wrought promises of sweeping concessions and reforms, a new Cabinet and a purge of the ruling party leadership.

The strikes broke out across Egypt as many companies reopened for the first time since night curfews were imposed almost two weeks ago. Not all the strikers were responding directly to the protesters' calls. But the movement's success and its denunciations of the increasing poverty under Mubarak's rule resonated and reignited labor discontent that has broken out frequently in recent years.

In one of the flashpoints of unrest Wednesday, some 8,000 protesters, mainly farmers, set barricades of flaming palm trees in the southern province of Assiut. They blocked the main highway and railway to Cairo to complain of bread shortages. They then drove off the governor by pelting his van with stones.

Hundreds of slum dwellers in the Suez Canal city of Port Said set fire to part of the governor's headquarters in anger over lack of housing.

The farmers in Assiut voiced their support for the Tahrir movement, witnesses said, as did the Port Said protesters, who set up a tent camp in the city's main Martyrs Square similar to the Cairo camp.

In Cairo, hundreds of state electricity workers stood in front of the South Cairo Electricity company, demanding the ouster of its director. Public transport workers at five of the city's roughly 17 garages also called strikes, demanding Mubarak's overthrow, and vowed that buses would be halted Thursday. It was not clear if they represented the entire bus system for this city of 18 million.

Dozens of state museum workers demanding higher wages staged a protest in front of the Supreme Council of Antiquities, crowding around antiquities chief Zahi Hawass when he came to talk to them.

Several hundred workers also demonstrated at a silk factory and a fuel coke plant in Cairo's industrial suburb of Helwan, demanding better pay and work conditions.

In the desert oasis town of Kharga, southwest of Cairo, five protesters have been killed in two days of rioting, security officials said. Police opened fire Tuesday on hundreds who set a courthouse on fire and attacked a police station, demanding the removal of the provincial security chief. The army was forced to secure several government buildings and prisons, and on Wednesday the security chief was dismissed, security officials said. They spoke on condition of anonymity because they were not authorized to talk to the media.

U.S.-based Human Rights Watch has said about 300 people have been killed since the protests began on Jan. 25, but it is still compiling a final toll.

In the city of Suez, strikes entered a second day on Wednesday. Some 5,000 workers at various state companies — including a textile workers, medicine bottle manufacturers, sanitation workers and a firm involved in repairs for ships on the Suez Canal — held separate strikes and protests at their factories.

Traffic at the Suez Canal, a vital international waterway that is a top revenue earner for Egypt, was not affected.

"We're not getting our rights," said Ahmed Tantawi, a Public Works employee in Suez. He said workers provide 24-hour service and are exposed to health risks but get only an extra $1.50 a month in hardship compensation. He said there are employees who have worked their entire lives in the department and will retire with a salary equivalent to $200 a month.

In Tahrir Square, the epicenter of the anti-government protests, about 10,000 massed again on Wednesday, the day after a crowd of about a quarter-million proved that they had not lost momentum even as Mubarak clings to power. Visitors snapped pictures and took videos while vendors sold nuts, popcorn, Egyptian flags, sandwiches and drinks.

Nearby, 2,000 more protesters blocked off parliament, several blocks away, chanting slogans for it to be dissolved. A huge caricature of Mubarak hung on the gates of parliament and army troops were on the grounds.

Organizers called for a new "protest of millions" for Friday similar to those that have drawn the largest crowds so far. But in a change of tactic, they want to spread the protests out around different parts of Cairo instead of only in the downtown square where a permanent sit-in is now in its second week, said Khaled Abdel-Hamid, one of the youth organizers.

Support for the protesters has come from another unlikely corner — Egypt's state-owned Al-Ahram newspaper. The mouthpiece of successive regimes since the 1950s, the paper has sharply changed the tone of its unrest coverage and is using the word "revolution" to describe the anti-Mubarak demonstrations. Since protests began on Jan. 25, the newspaper, Egypt's oldest, echoed official statements that called the protesters "outlaws" or "saboteurs" and a "bunch of conspirators."

Efforts by Vice President Suleiman to open a dialogue with protesters over reforms have broken down since the weekend, with youth organizers of the movement deeply suspicious that he plans only superficial changes far short of real democracy. They refuse any talks unless Mubarak steps down first.

Showing growing impatience with the rejection, Suleiman issued a sharp warning that raised the prospect of a renewed crackdown. He told Egyptian newspaper editors late Tuesday that there could be a "coup" unless demonstrators agree to enter negotiations.

Although it was not completely clear what he meant by "coup," protesters heard it as a veiled threat to impose martial law — which would be a dramatic escalation in the standoff.

"We can't bear this for a long time," Suleiman said of the protests. "There must be an end to this crisis as soon as possible." He said the regime wants to resolve the crisis through dialogue, warning: "We don't want to deal with Egyptian society with police tools

Officials have made a series of pledges not to attack, harass or arrest the activists in recent days. But Suleiman's comments suggested that won't last forever.

"He is threatening to impose martial law, which means everybody in the square will be smashed," said Abdul-Rahman Samir, a spokesman for a coalition of the five main youth groups behind protests in Cairo's Tahrir Square. "But what would he do with the rest of the 70 million Egyptians who will follow us afterward."

Suleiman is creating "a disastrous scenario," Samir said. "We are striking and we will protest and we will not negotiate until Mubarak steps down. Whoever wants to threaten us, then let them do so," he added.

Suleiman, a military man who was intelligence chief before being elevated to vice president amid the crisis, tried to explain the coup remark by saying:

"I mean a coup of the regime against itself, or a military coup or an absence of the system. Some force, whether its the army or police or the intelligence agency or the (opposition Muslim) Brotherhood or the youth themselves could carry out 'creative chaos' to end the regime and take power," he said.

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Suleiman, a close confident of the president, rejected any "end to the regime" including an immediate departure for Mubarak, who says he will serve out the rest of his term until September elections. Suleiman reiterated his view that Egypt is not ready for democracy.

Suleiman suggested Egypt was not ready for democracy, and said a government-formed panel of judges, dominated by Mubarak loyalists, would push ahead with recommending its own constitutional amendments to be put to a referendum. Those statements further deepened skepticism over his intentions.

Still, authorities continued to try to project an image of normalcy. Egypt's most famous tourist attraction, the Pyramids of Giza, reopened to tourists on Wednesday after a 12-day closure. But few came to visit — tens of thousands of foreigners have fled Egypt amid the chaos, raising concerns about the economic impact of the protests. Also Mubarak met Wednesday with a Russian envoy.

Associated Press writers Hadeel al-Shalchi, Hamza Hendawi, Paul Schemm, Maggie Hyde and Maamoun Youssef contributed to this report.