Stem-cell step spurs new debate

NEW YORK — Find a way to make stem cells without destroying an embryo and you might resolve one of the nation's fiercest public debates.

A biotech company seems to have done it. But early signs are the scientific achievement is not the slam-dunk solution the company had hoped.

Stem-cell opponents said Wednesday that the new method still doesn't satisfy their objections. And on the other side, many scientists and supporters of federal funding for the research called the technique inefficient and politically wrong-headed.

But a spokeswoman for President Bush, who last month vetoed legislation that would have allowed federal money for embryonic stem-cell research, called it a step in the right direction.

And Dr. Robert Lanza, an executive with Advanced Cell Technology, which created the new stem-cell lines, said, "This will make it far more difficult to oppose this research."

Stem cells have become a Holy Grail for advocates of patients with a wide variety of illnesses because of the cells' potential to transform into any type of human tissue, perhaps leading to new treatments. But the Vatican, President Bush and others have argued that the promise of stem cells should not be realized at the expense of human life, even in its most nascent stages.

The new method works by taking an embryo at a very early stage of development and removing a single cell, which can be coaxed into spawning an embryonic stem-cell line. With only one cell removed, the rest of the embryo retains its full potential for development.

The method was described online Wednesday in the British journal Nature. The journal published a similar paper by Advanced Cell Technology last year demonstrating the technique's viability in mice.

"The science is interesting and important," said John Harris, a professor of bioethics at the University of Manchester in Great Britain, commenting on the biotech company's efforts.

But few believe it will resolve the bitter ethical battle over stem-cell research.

"This will please no one," predicted a longtime critic of the company, Glenn McGee, director of the Alden March Bioethics Institute in Albany, N.Y.

Some stem-cell researchers complain that the new approach, though it may hold future promise, simply isn't as efficient as their current method of creating stem cells. That procedure involves the destruction of embryos after about five days of development, when they consist of about 100 cells.