Ramirez hits 400th homer of his career

SEATTLE — Boston's Manny Ramirez hit his 400th career home run Sunday, a three-run shot in the fifth inning off Seattle starter Gil Meche.

Ramirez is the 39th player in major league history to reach 400 homers, and just the fifth to reach the mark in a Red Sox uniform. The others were Jimmie Foxx, Ted Williams, Carl Yastrzemski and Andre Dawson.

Ramirez hit a 1-1 fastball from Meche an estimated 404 feet into the seats in right-center field. It was his 10th homer of the season and second in the three-game series with Seattle.

Ramirez is the 13th player to reach the mark before his 33rd birthday and just the fourth since Harmon Killebrew in 1969. He is the fifth-fastest to 400 in number of at-bats, behind Mark McGwire, Babe Ruth, Killebrew and Jim Thome.