Morgan said the study looks at crime only within St. Louis city limits, with a population of about 330,000. It doesn't take into account the suburbs in St. Louis County, which has roughly 980,000 residents.

The safest city in 2005 was Brick, N.J., population about 78,000, followed by Amherst, N.Y., and Mission Viejo, Calif. The second most dangerous city was Detroit, followed by Flint, Mich., and Compton, Calif.

Cities are ranked based on more than just their crime rate, Morgan said. Individual crimes such as rape or burglary are measured separately, compared to national averages and then compiled to give a city its ranking. Crimes are weighted based on their danger to people.

The national FBI figures released in June showed the murder rate in St. Louis jumped 16 percent in 2005, compared with 4.8 percent nationally. The overall violent crime rate increased nearly 20 percent, compared with 2.5 percent nationally.

While crime increased in all regions last year, the 5.7 percent rise in the 12 Midwestern states was at least three times higher than any other region, according to the FBI.

Visiting St. Louis on Thursday, FBI director Robert Mueller said it was too early to tell why some types of crime were rising faster in the Midwest.

Mueller said the FBI is working harder to form partnerships with police departments to launch programs like St. Louis' Safe Streets task force, which focuses police efforts on problematic neighborhoods.

This year's ranking was good news for Camden, N.J., which in 2005 was named the most dangerous city for the second year in a row.

Camden Mayor Gwendolyn Faison said Sunday she was thrilled to learn that her city no longer topped the most-dangerous list.

"You made my day!" said Faison, who has served since 2000. "There's a new hope and a new spirit."